Cell Marque Portfolio

Cytokeratin 10 (EP97)

Rabbit Monoclonal


Cytokeratin 10 (CK10)  belongs to type I and acidic keratin family.1 It is low molecular weight keratin that is usually expressed in suprabasal keratinocytes and can also be seen in suprabasal cells of internal noncornifying, stratified squamous epithelia.1 In addition, CK10 is reported to be a typical component of cells of eccrine sweat gland ducts and sebaceous cells.2 Anti-CK10 is helpful in the identification of well differentiated squamous cell carcinoma derived from skin or from internal organs.2,3 However, CK10 was found to be sparse in poorly differentiated squamous cell carcinoma, even though it has been reported that focal CK10 expression has been found in 50% of cases of oral and pharyngeal squamous cell carcinoma.3 Anti-CK10 has demonstrated utility in the differentiation of extra-mammary Paget’s disease (negative) from basal cell carcinoma and squamous cell carcinoma (positive).

Specialties: Anatomic Pathology

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: squamous cell carcinoma
  • Isotype: IgG
  • Dilution Range: 1:25-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/16min @ 37°C
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

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Cytokeratin 10
Cytokeratin 10 (EP97) on skin.

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Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: squamous cell carcinoma
  • Isotype: IgG
  • Dilution Range: 1:25-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/16min @ 37°C
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Download an IFU

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

DescriptionCat. No.
0.1 ml, concentrate 410R-14
0.5 ml, concentrate 410R-15
1 ml, concentrate 410R-16
1 ml, predilute 410R-17
7 ml, predilute 410R-18

For in vitro diagnostic (IVD) use in Canada

DescriptionCat. No.
0.1 ml, concentrate 410R-14
0.5 ml, concentrate 410R-15
1 ml, concentrate 410R-16
1 ml, predilute 410R-17
7 ml, predilute 410R-18

For in vitro diagnostic (IVD) use in the EU

DescriptionCat. No.
0.1 ml, concentrate 410R-14
0.5 ml, concentrate 410R-15
1 ml, concentrate 410R-16
1 ml, predilute 410R-17
7 ml, predilute 410R-18

For research use only (RUO) in Japan

DescriptionCat. No.
0.1 ml, concentrate 410R-14 (RUO)
0.5 ml, concentrate 410R-15 (RUO)
1 ml, concentrate 410R-16 (RUO)
1 ml, predilute 410R-17 (RUO)
7 ml, predilute 410R-18 (RUO)

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: squamous cell carcinoma
  • Isotype: IgG
  • Dilution Range: 1:25-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/16min @ 37°C
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Download an IFU

Select revision:


Keycode Specific IFU

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

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