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Napsin A (MRQ-60)

Mouse Monoclonal


Napsin is a pepsin-like aspartic proteinase, in the A1 clan of the AA clade of proteinases. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein with the molecular weight of approximately 38 kDa.  Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.1-5

Specialties: Cytopathology Pulmonary Pathology

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: lung adenocarcinoma, kidney, renal cell carcinoma
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/8min @ 37°C
  • Ventana ultraView
    UV/CC1M/16min @ 37°C
  • Leica Bond
    Protocol F: ER2/20

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Last updated: 2016-09-29 13:18:40

Napsin A
Lung adenocarcinoma tumor cells are stained by anti-napsin A.

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Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: lung adenocarcinoma, kidney, renal cell carcinoma
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/8min @ 37°C
  • Ventana ultraView
    UV/CC1M/16min @ 37°C
  • Leica Bond
    Protocol F: ER2/20

Download an IFU

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

DescriptionCat. No.
0.1 ml, concentrate 352M-94
0.5 ml, concentrate 352M-95
1 ml, concentrate 352M-96
1 ml, predilute 352M-97
7 ml, predilute 352M-98
25 ml, predilute 352M-90

For in vitro diagnostic (IVD) use in Canada

DescriptionCat. No.
0.1 ml, concentrate 352M-94
0.5 ml, concentrate 352M-95
1 ml, concentrate 352M-96
1 ml, predilute 352M-97
7 ml, predilute 352M-98
25 ml, predilute 352M-90

For in vitro diagnostic (IVD) use in the EU

DescriptionCat. No.
0.1 ml, concentrate 352M-94
0.5 ml, concentrate 352M-95
1 ml, concentrate 352M-96
1 ml, predilute 352M-97
7 ml, predilute 352M-98
25 ml, predilute 352M-90

For research use only (RUO) in Japan

DescriptionCat. No.
0.1 ml, concentrate 352M-94 (RUO)
0.5 ml, concentrate 352M-95 (RUO)
1 ml, concentrate 352M-96 (RUO)
1 ml, predilute 352M-97 (RUO)
7 ml, predilute 352M-98 (RUO)
25 ml, predilute 352M-90 (RUO)

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: lung adenocarcinoma, kidney, renal cell carcinoma
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/8min @ 37°C
  • Ventana ultraView
    UV/CC1M/16min @ 37°C
  • Leica Bond
    Protocol F: ER2/20

Download an IFU

Select revision:


Keycode Specific IFU

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

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