Mouse monoclonal CA IX antibody shows a strong membranous expression of the CA IX protein in renal cell carcinoma.
Carbonic Anhydrase IX (CA IX) (MRQ-54) Mouse Monoclonal Antibody
Specialties: Anatomic Pathology
Updated: 2017-05-24 08:50:18
Carbonic Anhydrase (CA IX) is part of a family of zinc containing metalloproteins that catalyze the reversible hydration of CO2.1 Among these, CA IX is anchored to the cell membrane and is expressed in the human gastrointestinal tract, chiefly in the stomach.1 Data suggest consistent immunoreactivity for anti-CA IX in clear cell renal cell carcinoma (RCC) making it a useful marker for this type of tumor.2
- Leppilampi, M et al. Carbonic anhydrase isozymes IX and XII in gastric tumors. World J Gastroenterol. 2003; 9:1398-1403.
- Gupta, R et al. Diagnostic implications of transcription factor Pax 2 protein and transmembrane enzyme complex carbonic anhydrase IX immunoreactivity in adult renal epithelial neoplasms. Am J Surg Pathol. 2009; 33:241-7.
Specifications
- Reactivity: paraffin
- Visualization: membranous
- Control: clear cell renal cell carcinoma, gall bladder epithelium
- Dilution Range: 1:50-1:200*
Package Inserts
IFU
- IVD Rev. 1.0 (CMC37921010)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 379M-14 |
| 0.5 mL concentrate | 379M-15 |
| 1 mL concentrate | 379M-16 |
| 1 mL predilute | 379M-17 |
| 7 mL predilute | 379M-18 |
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