FoxP1 (SP133) Rabbit Monoclonal Antibody

FoxP1
FoxP1 (SP133) on lymph node.

FoxP1 (SP133) Rabbit Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-09-20 09:32:39

Forkhead box P1 (FOXP1) is a transcription factor normally expressed in many cellular processes and plays an important role in development, specifically in human leukocyte populations.1,2 Expression of FOXP1 can be found in neoplastic and non-neoplastic tissues.2  Overexpression of FOXP1 has been observed in a subset of diffuse large B-cell lymphoma (DLBCL), and thus FOXP1 immunohistochemistry has been shown to be helpful in the subclassification of DLBCL.2

  1. Garaud S, et al. FOXP1 is a regulator of quiescence in healthy human CD4+ T cells and is constitutively repressed in T cells from patients with lymphoproliferative disorders. Eur. J. Immunol. 2017; 47:168-79.
  2. Wlodarska I, et al. FOXP1, a gene highly expressed in a subset of diffuse large B-cell lymphoma, is recurrently targeted by genomic aberrations. Leukemia. 2005; 19:1299-305.

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: tonsil, lymph node
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate350R-14
0.5 mL concentrate350R-15
1 mL concentrate350R-16
1 mL predilute350R-17
7 mL predilute350R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate350R-14
0.5 mL concentrate350R-15
1 mL concentrate350R-16
1 mL predilute350R-17
7 mL predilute350R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate350R-14
0.5 mL concentrate350R-15
1 mL concentrate350R-16
1 mL predilute350R-17
7 mL predilute350R-18

For research use only (RUO) in Japan

0.1 mL concentrate350R-14-RUO
0.5 mL concentrate350R-15-RUO
1 mL concentrate350R-16-RUO
1 mL predilute350R-17-RUO
7 mL predilute350R-18-RUO

 

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