Vimentin (SP20) Rabbit Monoclonal Antibody

Vimentin
Lymphocyte/germinal center cells are labelled by anti-vimentin.

Vimentin (SP20) Rabbit Monoclonal Antibody

Specialties: Anatomic Pathology

Updated: 2018-01-11 11:30:28

Anti-vimentin recognizes a 57-kDa intermediate filament initially isolated from mouse fibroblast culture. Anti-vimentin often serves as a useful control marker to ensure that the tissue has been properly preserved and processed.1 Expression of vimentin, when used in conjunction with keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas react strongly with vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. In the area of gynecologic tumors, uterine endometrioid adenocarcinomas display a highly characteristic immunophenotype, with coexpression of low molecular wt. cytokeratin and vimentin.1-4

  1. Dabbs DJ. Diagnositc Immunohistochemistry. Third Edition. Philadelphia, PA: Saunders/Elsevier. 2010. Print.
  2. Dabbs DJ, et al. The immunohistochemical discrimination of endometrioid adenocarcinomas. Hum Pathol. 1996; 27:172-7.
  3. Dabbs DJ, et al. Intermediate filaments in endometrial and endocervical carcinomas. The diagnostic utility of vimentin patterns. Am J Surg Pathol. 1986; 10:568-76.
  4. Yaziji H, et al. Immunohistochemical analysis of gynecologic tumors. Int J Gynecol Pathol. 2001; 20:64-78.

Specifications


  • Reactivity: paraffin
  • Control: Tonsil (Cytoplasmic)
  • Dilution Range: 1:100-1:500 *

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate347R-14
0.5 mL concentrate347R-15
1.0 mL concentrate347R-16
1.0 mL predilute ready-to-use347R-17
7.0 mL predilute ready-to-use347R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate347R-14
0.5 mL concentrate347R-15
1.0 mL concentrate347R-16
1.0 mL predilute ready-to-use347R-17
7.0 mL predilute ready-to-use347R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate347R-14
0.5 mL concentrate347R-15
1.0 mL concentrate347R-16
1.0 mL predilute ready-to-use347R-17
7.0 mL predilute ready-to-use347R-18

For research use only (RUO) in Japan

0.1 mL concentrate (RUO)347R-14-RUO
0.5 mL concentrate (RUO)347R-15-RUO
1.0 mL concentrate (RUO)347R-16-RUO
1.0 mL predilute ready-to-use (RUO)347R-17-RUO
7.0 mL predilute ready-to-use (RUO)347R-18-RUO

 

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