Hemoglobin A (EPR3608) Rabbit Monoclonal Antibody

Hemoglobin A
Hemoglobin A antibody finds hemoglobin A protein in the cytoplasms of mature red cells and erythroid percursors in the bone marrow.

Hemoglobin A (EPR3608) Rabbit Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-06-02 08:21:46

Hemoglobin alpha chain belongs to the globin family and is involved in oxygen transport from the lung to the various peripheral tissues. Hemoglobin A is comprised of two alpha chains and two beta chains.1 Immunohistochemical localization of hemoglobin is excellent as an erythroid marker for the detection of immature, dysplastic, and megaloblastic erythroid cells in myeloproliferative disorders, such as erythroleukemia. In contrast, myeloid cells, lymphoid cells, plasma cells, histiocytes, and megakaryocytes do not stain with anti-hemoglobin A.2

  1. Wynbrandt J, et al. The encyclopedia of genetic disorders and birth defects, Third Edition. Facts on File, Inc. New York. 2008. Print.
  2. O’Malley DP, et al. Morphologic and immunohistochemical evaluation of splenic hematopoietic proliferations in neoplastic and benign disorders. Mod Pathol. 2005; 18:1550-61.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: bone marrow, spleen
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate360R-14
0.5 mL concentrate360R-15
1 mL concentrate360R-16
1 mL predilute360R-17
7 mL predilute360R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate360R-14
0.5 mL concentrate360R-15
1 mL concentrate360R-16
1 mL predilute360R-17
7 mL predilute360R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate360R-14
0.5 mL concentrate360R-15
1 mL concentrate360R-16
1 mL predilute360R-17
7 mL predilute360R-18

For research use only (RUO) in Japan

0.1 mL concentrate360R-14-RUO
0.5 mL concentrate360R-15-RUO
1 mL concentrate360R-16-RUO
1 mL predilute360R-17-RUO
7 mL predilute360R-18-RUO

 

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