GCDFP-15 (23A3) + Mammaglobin Cocktail (304-1A5 & 31A5) Mouse/Rabbit Monoclonal Antibodies

GCDFP-15 (23A3) + Mammaglobin Cocktail (304-1A5 & 31A5)
GCDFP-15 + Mammaglobin Cocktail (23A3 + 304-1A5 & 31A5) on infiltrating ductal carcinoma of the breast.

GCDFP-15 (23A3) + Mammaglobin Cocktail (304-1A5 & 31A5) Mouse/Rabbit Monoclonal Antibodies

Specialties: Breast/Gynecological Pathology

Updated: 2017-05-24 08:46:09

Anti-GCDFP-15, mouse monoclonal (23A3), and anti-mammaglobin, mouse monoclonal (304-1A5) and rabbit monoclonal (31A5), is an antibody cocktail.  GCDFP-15 is a 15 kDa glycoprotein which is localized in the apocrine metaplastic epithelium lining breast cysts and in apocrine glands in the axilla, vulva, eyelid, and ear canal. Mammaglobin (10 kDa) is a breast-associated glycoprotein distantly related to the secretoglobin family that includes human uteroglobin and lipophilin.1-6 This antibody cocktail is useful in identifying breast carcinoma.4-6

  1. Cohen, C et al. Mammary Paget’s disease and associated carcinoma. An immunohistochemical study. Arch Pathol Lab Med. 1993; 117:291-4.
  2. Bhargava R, et al. Mammaglobin vs GCDFP-15: an immunohistologic validation survey for sensitivity and specificity. Am J Clin Pathol. 2007; 127:103-13.
  3. Tornos C, et al. Expression of WT1, CA 125, and GCDFP-15 as useful markers in the differential diagnosis of primary ovarian carcinomas versus metastatic breast cancer to the ovary. Am J Surg Pathol. 2005; 29:1482-9.
  4. Takeda Y, et al. Analysis of expression patterns of breast cancer-specific markers (mammaglobin and gross cystic disease fluid protein 15) in lung and pleural tumors. Arch Pathol Lab Med. 2008; 132:239-43.
  5. Liegl, B et al. Mammary and extramammary Paget’s disease: an immunohistochemical study of 83 cases. Histopathology. 2007; 50:439-47.
  6. Watson MA, et al. Mammaglobin expression in primary, metastatic, and occult breast cancer. Cancer Res. 1999; 59:3028-31.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: breast, breast carcinoma

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

1 mL predilute906H-07
7 mL predilute906H-08

For in vitro diagnostic (IVD) use in Canada

1 mL predilute906H-07
7 mL predilute906H-08

For in vitro diagnostic (IVD) use in Europe

1 mL predilute906H-07
7 mL predilute906H-08

For research use only (RUO) in Japan

1 mL predilute906H-07-RUO
7 mL predilute906H-08-RUO

 

To request information on this product in additional countries, please click the button below.

Request More Information