Claudin 1 Rabbit Polyclonal Antibody

Claudin 1
Anti-claudin 1 stains colon adenocarcinoma in a cell membranous pattern.

Claudin 1 Rabbit Polyclonal Antibody

Specialties: Anatomic Pathology

Updated: 2017-05-24 08:46:09

Claudins are a family of over twenty proteins which are components of tight junctions. Tight junctions are specialized regions of cell-to-cell contact made up of a network of strands to act as a molecular ‘gasket’ for preventing the leakage of ions, water, etc., between cells.1 Claudin 1 has been shown to distinguish epithelial neoplasms from lymphomas, making it a useful marker for nearly all carcinomas.2

  1. Folpe AL, et al. Expression of claudin-1, a recently described tight junction-associated protein, distinguishes soft tissue perineurioma from potential mimics. Am J Surg Pathol. 2002; 26:1620-6.
  2. Soini Y. Expression of claudins 1, 2, 3, 4, 5, and 7 in various types of tu­mors. Histopathology. 2005; 47:551-60.

Specifications


  • Reactivity: paraffin
  • Visualization: membranous
  • Control: neurofibroma, colon carcinoma
  • Dilution Range: 1:25-1:100*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate359A-14
0.5 mL concentrate359A-15
1 mL concentrate359A-16
1 mL predilute359A-17
7 mL predilute359A-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate359A-14
0.5 mL concentrate359A-15
1 mL concentrate359A-16
1 mL predilute359A-17
7 mL predilute359A-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate359A-14
0.5 mL concentrate359A-15
1 mL concentrate359A-16
1 mL predilute359A-17
7 mL predilute359A-18

For research use only (RUO) in Japan

0.1 mL concentrate359A-14-RUO
0.5 mL concentrate359A-15-RUO
1 mL concentrate359A-16-RUO
1 mL predilute359A-17-RUO
7 mL predilute359A-18-RUO

 

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