Mammaglobin Cocktail (304-1A5 & 31A5) Mouse/Rabbit Cocktail Antibody
Specialties: Breast/Gynecological Pathology
Mammaglobin (10 kD) is a breast-associated glycoprotein distantly related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin mRNA is present in high levels in human breast cancer cell lines, which has been shown to be a sensitive marker of breast cancer.1,2,3 When combined with other breast-restricted markers such as GCDFP-15, an overall increased sensitivity for breast carcinoma has been achieved.4-6
- Watson, et al. Mammaglobin expression in primary, metastatic, and occult cancer. Cancer Research. 1999; 59:3028-31.
- Fleming TP, et al. Mammaglobin, a breast-specific gene, and its utility as a marker for breast cancer. Ann N Y Acad Sci. 2000; 923:78-89.
- Han JH, et al. Mammaglobin expression in lymph nodes is an important marker of metastatic breast carcinoma. Arch Pathol Lab Med. 2003; 127:1330-4.
- Bhargava R, et al. Mammaglobin vs GCDFP-15: an immunohistologic validation survey for sensitivity and specificity. Am J Clin Pathol. 2007; 127:103-13
- Sasaki E, et al., Breast-specific expression of MGB1/ mammaglobin: an examination of 480 tumors from various organs and clinicopathological analysis of MGB1-positive breast cancers. Mod Pathol. 2007; 20:208-14.
- Wang Z, et al. Mammaglobin, a valuable diagnostic marker for metastatic breast carcinoma. Int J Clin Exp Pathol. 2009; 2:384-9.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic
- Control: breast carcinoma
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 6.0 (CMC28091060)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 280C-14 |
| 0.5 mL concentrate | 280C-15 |
| 1 mL concentrate | 280C-16 |
| 1 mL predilute | 280C-17 |
| 7 mL predilute | 280C-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 280C-14 |
| 0.5 mL concentrate | 280C-15 |
| 1 mL concentrate | 280C-16 |
| 1 mL predilute | 280C-17 |
| 7 mL predilute | 280C-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 280C-14 |
| 0.5 mL concentrate | 280C-15 |
| 1 mL concentrate | 280C-16 |
| 1 mL predilute | 280C-17 |
| 7 mL predilute | 280C-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 280C-14-RUO |
| 0.5 mL concentrate | 280C-15-RUO |
| 1 mL concentrate | 280C-16-RUO |
| 1 mL predilute | 280C-17-RUO |
| 7 mL predilute | 280C-18-RUO |
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