PAX-5 antibody has a strong nuclear expression for Reed-Sternberg cells and B-lymphocytes in Hodgkin lymphoma.
PAX-5 (SP34) Rabbit Monoclonal Antibody
Specialties: Hematopathology
Updated: 2017-05-24 08:46:09
PAX-5 encodes for transcription factor B-cell-specific activator protein (BSAP) and has a central role in B-cells proliferation and differentiation, as well as midbrain development1. Anti-PAX-5 has been shown to be a useful marker for B-cell malignancies.1-3
- O'Brien P, et al. The Pax-5 gene: a pluripotent regulator of B-cell differentiation and cancer disease. Cancer Res. 2011; 71:7345-50.
- Zhang X, et al. Pax5 expression in non-Hodgkin's lymphomas and acute leukemias. J Korean Med Sci. 2003; 18:804-8.
- Desouki MM, et al. PAX-5: a valuable immunohistochemical marker in the differential diagnosis of lymphoid neoplasms. Clin Med Res. 2010; 8:84-8.
Specifications
- Reactivity: paraffin
- Visualization: nuclear
- Control: tonsil
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 4.0 (CMC31231040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 312R-14 |
| 0.5 mL concentrate | 312R-15 |
| 1 mL concentrate | 312R-16 |
| 1 mL predilute | 312R-17 |
| 7 mL predilute | 312R-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 312R-14 |
| 0.5 mL concentrate | 312R-15 |
| 1 mL concentrate | 312R-16 |
| 1 mL predilute | 312R-17 |
| 7 mL predilute | 312R-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 312R-14 |
| 0.5 mL concentrate | 312R-15 |
| 1 mL concentrate | 312R-16 |
| 1 mL predilute | 312R-17 |
| 7 mL predilute | 312R-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 312R-14-RUO |
| 0.5 mL concentrate | 312R-15-RUO |
| 1 mL concentrate | 312R-16-RUO |
| 1 mL predilute | 312R-17-RUO |
| 7 mL predilute | 312R-18-RUO |
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