PAX-5 (SP34) Rabbit Monoclonal Antibody

PAX-5
PAX-5 antibody has a strong nuclear expression for Reed-Sternberg cells and B-lymphocytes in Hodgkin lymphoma.

PAX-5 (SP34) Rabbit Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-24 08:46:09

PAX-5 encodes for transcription factor B-cell-specific activator protein (BSAP) and has a central role in B-cells proliferation and differentiation, as well as midbrain development1. Anti-PAX-5 has been shown to be a useful marker for B-cell malignancies.1-3 

  1. O'Brien P, et al. The Pax-5 gene: a pluripotent regulator of B-cell differentiation and cancer disease. Cancer Res. 2011; 71:7345-50.
  2. Zhang X, et al. Pax5 expression in non-Hodgkin's lymphomas and acute leukemias. J Korean Med Sci. 2003; 18:804-8.
  3. Desouki MM, et al. PAX-5: a valuable immunohistochemical marker in the differential diagnosis of lymphoid neoplasms. Clin Med Res. 2010; 8:84-8.

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: tonsil
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate312R-14
0.5 mL concentrate312R-15
1 mL concentrate312R-16
1 mL predilute312R-17
7 mL predilute312R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate312R-14
0.5 mL concentrate312R-15
1 mL concentrate312R-16
1 mL predilute312R-17
7 mL predilute312R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate312R-14
0.5 mL concentrate312R-15
1 mL concentrate312R-16
1 mL predilute312R-17
7 mL predilute312R-18

For research use only (RUO) in Japan

0.1 mL concentrate312R-14-RUO
0.5 mL concentrate312R-15-RUO
1 mL concentrate312R-16-RUO
1 mL predilute312R-17-RUO
7 mL predilute312R-18-RUO

 

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