FLI-1 (MRQ-1) Mouse Monoclonal Antibody

FLI-1
FLI-1 (MRQ-1) on soft tissue.

FLI-1 (MRQ-1) Mouse Monoclonal Antibody

Specialties: Soft Tissue Pathology

Updated: 2017-05-24 08:46:09

Friend leukemia integration 1 transcription factor (FLI-1) is a protein encoded by the proto-ocogene FLI-1.  The FLI-1 protein is best known for its critical role in the pathogenesis of ES/pPNET. FLI-1 is normally expressed in endothelial cells and in hematopoietic cells, including T-lymphocytes. The immunohistochemical detection of FLI-1 protein has been shown in studies to be valuable in the discrimination of Ewing sarcoma/peripheral primitive neuroectodermal tumor (ES/pPNET) from most of its potential mimics. ES/pPNET is a rare primary tumor of the bone/soft tissue that resembles other undifferentiated tumors.1-3

  1. Mhawech-Fauceglia P, et al. Histopathology. 2006; 49:569-75.
  2. Kuroda N, et al. Med Mol Morphol. 2006; 39:221-5.
  3. Ellison DA, et al. Hum Pathol. 2007; 38:205-11.

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: primitive neuroectodermal tumor
  • Dilution Range: 1:25-1:100*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate254M-14
0.5 mL concentrate254M-15
1 mL concentrate254M-16
1 mL predilute254M-17
7 mL predilute254M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate254M-14
0.5 mL concentrate254M-15
1 mL concentrate254M-16
1 mL predilute254M-17
7 mL predilute254M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate254M-14
0.5 mL concentrate254M-15
1 mL concentrate254M-16
1 mL predilute254M-17
7 mL predilute254M-18

For research use only (RUO) in Japan

0.1 mL concentrate254M-14-RUO
0.5 mL concentrate254M-15-RUO
1 mL concentrate254M-16-RUO
1 mL predilute254M-17-RUO
7 mL predilute254M-18-RUO

 

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Literature

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