Cell Marque Portfolio

BCL2 (124)

Mouse Monoclonal


Anti-bcl-2 has shown consistent negative reaction on reactive germinal centers and positive staining of neoplastic follicles in follicular lymphoma. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. This antibody may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative. Anti-bcl-2 has been used as a predictive biomarker for recurrence in the case of radical prostatectomy for prostate cancer, and has shown promise as a prognostic marker in the case of cancer of the breast and non-small cell carcinoma of the lung.

Specialties: Hematopathology

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: tonsil
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

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Keycode Specific IFU

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*Note: IFUs with the prefix RUO or ASR are only available for download in English.


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References


  1. Tsujimoto Y, et al. Proc Natl Acad Scie (USA). 1986; 83:5214-5218.
  2. Cleary ML, et al. Cell. 1986; 47:19-28.
  3. Pezzella F, et al. Am J Pathol. 1990; 137:225-232.
  4. Hockenbery D, et al. Nature. 1990; 348:334-336.
  5. Moul JW, et al. Eur Urol. 1999; 35:399-407.
  6. Ciocca DR, et al. Endocrine. 2000; 13:1-10.
  7. Martin B, et al. Br J Cancer. 2003; 89:55-64.

Last updated: 2015-11-23 14:40:38

BCL2
BCL2 (124) on tonsil.

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Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: tonsil
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

References


  1. Tsujimoto Y, et al. Proc Natl Acad Scie (USA). 1986; 83:5214-5218.
  2. Cleary ML, et al. Cell. 1986; 47:19-28.
  3. Pezzella F, et al. Am J Pathol. 1990; 137:225-232.
  4. Hockenbery D, et al. Nature. 1990; 348:334-336.
  5. Moul JW, et al. Eur Urol. 1999; 35:399-407.
  6. Ciocca DR, et al. Endocrine. 2000; 13:1-10.
  7. Martin B, et al. Br J Cancer. 2003; 89:55-64.

Download an IFU

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

DescriptionCat. No.
0.1 ml, concentrate 226M-94
0.5 ml, concentrate 226M-95
1 ml, concentrate 226M-96
1 ml, predilute 226M-97
7 ml, predilute 226M-98
25 ml, predilute 226M-90

For in vitro diagnostic (IVD) use in Canada

DescriptionCat. No.
0.1 ml, concentrate 226M-94
0.5 ml, concentrate 226M-95
1 ml, concentrate 226M-96
1 ml, predilute 226M-97
7 ml, predilute 226M-98
25 ml, predilute 226M-90

For in vitro diagnostic (IVD) use in the EU

DescriptionCat. No.
0.1 ml, concentrate 226M-94
0.5 ml, concentrate 226M-95
1 ml, concentrate 226M-96
1 ml, predilute 226M-97
7 ml, predilute 226M-98
25 ml, predilute 226M-90

For research use only (RUO) in Japan

DescriptionCat. No.
0.1 ml, concentrate 226M-94 (RUO)
0.5 ml, concentrate 226M-95 (RUO)
1 ml, concentrate 226M-96 (RUO)
1 ml, predilute 226M-97 (RUO)
7 ml, predilute 226M-98 (RUO)
25 ml, predilute 226M-90 (RUO)

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: tonsil
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Download an IFU

Select revision:


Keycode Specific IFU

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

References


  1. Tsujimoto Y, et al. Proc Natl Acad Scie (USA). 1986; 83:5214-5218.
  2. Cleary ML, et al. Cell. 1986; 47:19-28.
  3. Pezzella F, et al. Am J Pathol. 1990; 137:225-232.
  4. Hockenbery D, et al. Nature. 1990; 348:334-336.
  5. Moul JW, et al. Eur Urol. 1999; 35:399-407.
  6. Ciocca DR, et al. Endocrine. 2000; 13:1-10.
  7. Martin B, et al. Br J Cancer. 2003; 89:55-64.
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