Calponin-1 (EP798Y) Rabbit Monoclonal Antibody

Calponin-1
Myoepithelial cells of breast sclerosing adenosis are stained positive in a cytoplasmic pattern.

Calponin-1 (EP798Y) Rabbit Monoclonal Antibody

Specialties: Anatomic Pathology

Updated: 2017-05-24 08:46:09

Calponin is a 34 kD polypeptide that interacts with actin, tropomyosin, and calmodulin. It is involved in smooth muscle contraction mechanism and is restricted exclusively to smooth muscle tissue. Anti-calponin has been found to be useful in staining myoepithelium and is, therefore, useful for differentiating benign sclerosing adenosis of the breast from infiltrating ductal carcinoma.1 Calponin positivity has also been noted in malignant myoepithelioma2,5 and pleomorphic adenoma3 of salivary gland origin, as well as angiomatoid malignant fibrous histiocytoma.4

  1. Wang NP, et al. Appl Immunohistochem. 1997; 5:141-151.
  2. Nagao T, et al. Cancer. 1998; 83:1292-9.
  3. Savara AT, et al. Mod Pathol. 1997; 10:1093-1100.
  4. Fanburg-Smith JC, et al. Hum Pathol. 1999; 30:1336-43.
  5. Hornick JL, et al. Am J Surg Pathol. 2003; 27: 1183-96.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: appendix
  • Dilution Range: 1:50-1:200*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate231R-14
0.5 mL concentrate231R-15
1 mL concentrate231R-16
1 mL predilute231R-17
7 mL predilute231R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate231R-14
0.5 mL concentrate231R-15
1 mL concentrate231R-16
1 mL predilute231R-17
7 mL predilute231R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate231R-14
0.5 mL concentrate231R-15
1 mL concentrate231R-16
1 mL predilute231R-17
7 mL predilute231R-18

For research use only (RUO) in Japan

0.1 mL concentrate231R-14-RUO
0.5 mL concentrate231R-15-RUO
1 mL concentrate231R-16-RUO
1 mL predilute231R-17-RUO
7 mL predilute231R-18-RUO

 

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