Cell Marque Portfolio

Podoplanin (D2-40)

Mouse Monoclonal


Podoplanin is a transmembrane mucoprotein (38kD) recognized by the D2-40 monoclonal antibody.1 Podoplanin is selectively expressed in lymphatic endothelium1-6 as well as lymphangiomas,7 Kaposi sarcomas,6,8 and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.1,9,10

Specialties: Anatomic Pathology

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: tonsil
  • Isotype: IgG1
  • Dilution Range: 1:20-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C
  • Leica Bond
    Protocol F: ER1/30

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Literature

Last updated: 2016-09-29 13:18:40

Podoplanin
Abundant cytoplasmic labelling on seminoma by podoplanin antibody.

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Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: tonsil
  • Isotype: IgG1
  • Dilution Range: 1:20-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C
  • Leica Bond
    Protocol F: ER1/30

Download an IFU

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

DescriptionCat. No.
0.1 ml, concentrate 322M-14
0.5 ml, concentrate 322M-15
1 ml, concentrate 322M-16
1 ml, predilute 322M-17
7 ml, predilute 322M-18
25 ml, predilute 322M-10

For in vitro diagnostic (IVD) use in Canada

DescriptionCat. No.
0.1 ml, concentrate 322M-14
0.5 ml, concentrate 322M-15
1 ml, concentrate 322M-16
1 ml, predilute 322M-17
7 ml, predilute 322M-18
25 ml, predilute 322M-10

For in vitro diagnostic (IVD) use in the EU

DescriptionCat. No.
0.1 ml, concentrate 322M-14
0.5 ml, concentrate 322M-15
1 ml, concentrate 322M-16
1 ml, predilute 322M-17
7 ml, predilute 322M-18
25 ml, predilute 322M-10

For research use only (RUO) in Japan

DescriptionCat. No.
0.1 ml, concentrate 322M-14 (RUO)
0.5 ml, concentrate 322M-15 (RUO)
1 ml, concentrate 322M-16 (RUO)
1 ml, predilute 322M-17 (RUO)
7 ml, predilute 322M-18 (RUO)
25 ml, predilute 322M-10 (RUO)

Literature

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: tonsil
  • Isotype: IgG1
  • Dilution Range: 1:20-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C
  • Leica Bond
    Protocol F: ER1/30

Download an IFU

Select revision:


Keycode Specific IFU

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

Request More Information