Cell Marque Portfolio

Mammaglobin (31A5)

Rabbit Monoclonal


Mammaglobin is breast-associated glycoprotein distantly related to secretoglobin family that includes human uteroglobin and lipophilin.1,2 Anti-mammaglobin labels cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas.1-4 Absence of mammaglobin expression is typically seen in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung and thyroid tissue.2,5 Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.2,3

Specialties: Breast/Gynecological Pathology

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: breast carcinoma
  • Isotype: IgG
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C
  • Leica Bond
    Protocol F: ER1/30

Package Inserts


IFU SDS

References


  1. Fleming TP, et al. Mammaglobin, a breast-specific gene, and its utility as a marker for breast cancer. Ann N Y Acad Sci. 2000; 923:78-89.
  2. Bhargava R, et al. Mammaglobin vs GCDFP-15: an immunohistologic validation survey for sensitivity and specificity. Am J Clin Pathol. 2007; 127:103-13.
  3. Wang Z, et al. Mammaglobin, a valuable diagnostic marker for metastatic breast carcinoma. Int J Clin Exp Pathol. 2009; 2:384-9.
  4. Han JH, et al. Mammaglobin expression in lymph nodes is an important marker of metastatic breast carcinoma. Arch Pathol Lab Med. 2003; 127:1330-4.
  5. Zafrakas M, et al. Expression analysis of mammaglobin A (SCGB2A2) and lipophilin B (SCGB1D2) in more than 300 human tumors and matching normal tissues reveals their co-expression in gynecologic malignancies. BMC Cancer. 2006; 6:88.

Last updated: 2017-05-24 08:46:09

Mammaglobin
Mammaglobin (31A5) on breast.

Mouse over to zoom, use scroll wheel to zoom in/out

Tap image once to activate zoom lens


Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: breast carcinoma
  • Isotype: IgG
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C
  • Leica Bond
    Protocol F: ER1/30

References


  1. Fleming TP, et al. Mammaglobin, a breast-specific gene, and its utility as a marker for breast cancer. Ann N Y Acad Sci. 2000; 923:78-89.
  2. Bhargava R, et al. Mammaglobin vs GCDFP-15: an immunohistologic validation survey for sensitivity and specificity. Am J Clin Pathol. 2007; 127:103-13.
  3. Wang Z, et al. Mammaglobin, a valuable diagnostic marker for metastatic breast carcinoma. Int J Clin Exp Pathol. 2009; 2:384-9.
  4. Han JH, et al. Mammaglobin expression in lymph nodes is an important marker of metastatic breast carcinoma. Arch Pathol Lab Med. 2003; 127:1330-4.
  5. Zafrakas M, et al. Expression analysis of mammaglobin A (SCGB2A2) and lipophilin B (SCGB1D2) in more than 300 human tumors and matching normal tissues reveals their co-expression in gynecologic malignancies. BMC Cancer. 2006; 6:88.

Package Inserts

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

25 mL predilute 280R-10
0.1 mL concentrate 280R-14
0.5 mL concentrate 280R-15
1 mL concentrate 280R-16
1 mL predilute 280R-17
7 mL predilute 280R-18

For in vitro diagnostic (IVD) use in Canada

25 mL predilute 280R-10
0.1 mL concentrate 280R-14
0.5 mL concentrate 280R-15
1 mL concentrate 280R-16
1 mL predilute 280R-17
7 mL predilute 280R-18

For in vitro diagnostic (IVD) use in Europe

25 mL predilute 280R-10
0.1 mL concentrate 280R-14
0.5 mL concentrate 280R-15
1 mL concentrate 280R-16
1 mL predilute 280R-17
7 mL predilute 280R-18

For research use only (RUO) in Japan

25 mL predilute 280R-10-RUO
0.1 mL concentrate 280R-14-RUO
0.5 mL concentrate 280R-15-RUO
1 mL concentrate 280R-16-RUO
1 mL predilute 280R-17-RUO
7 mL predilute 280R-18-RUO

 

For more information about this product in your area, contact us by clicking the button below.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: breast carcinoma
  • Isotype: IgG
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C
  • Leica Bond
    Protocol F: ER1/30

Download Package Insert

Select revision:


Keycode Specific Package Insert

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

Download SDS

References


  1. Fleming TP, et al. Mammaglobin, a breast-specific gene, and its utility as a marker for breast cancer. Ann N Y Acad Sci. 2000; 923:78-89.
  2. Bhargava R, et al. Mammaglobin vs GCDFP-15: an immunohistologic validation survey for sensitivity and specificity. Am J Clin Pathol. 2007; 127:103-13.
  3. Wang Z, et al. Mammaglobin, a valuable diagnostic marker for metastatic breast carcinoma. Int J Clin Exp Pathol. 2009; 2:384-9.
  4. Han JH, et al. Mammaglobin expression in lymph nodes is an important marker of metastatic breast carcinoma. Arch Pathol Lab Med. 2003; 127:1330-4.
  5. Zafrakas M, et al. Expression analysis of mammaglobin A (SCGB2A2) and lipophilin B (SCGB1D2) in more than 300 human tumors and matching normal tissues reveals their co-expression in gynecologic malignancies. BMC Cancer. 2006; 6:88.
Request More Information