Mammaglobin (31A5) Rabbit Monoclonal Antibody

Mammaglobin
Mammaglobin (31A5) on breast.

Mammaglobin (31A5) Rabbit Monoclonal Antibody

Specialties: Breast/Gynecological Pathology

Updated: 2017-05-24 08:46:09

Mammaglobin is breast-associated glycoprotein distantly related to secretoglobin family that includes human uteroglobin and lipophilin.1,2 Anti-mammaglobin labels cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas.1-4 Absence of mammaglobin expression is typically seen in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung and thyroid tissue.2,5 Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.2,3

  1. Fleming TP, et al. Mammaglobin, a breast-specific gene, and its utility as a marker for breast cancer. Ann N Y Acad Sci. 2000; 923:78-89.
  2. Bhargava R, et al. Mammaglobin vs GCDFP-15: an immunohistologic validation survey for sensitivity and specificity. Am J Clin Pathol. 2007; 127:103-13.
  3. Wang Z, et al. Mammaglobin, a valuable diagnostic marker for metastatic breast carcinoma. Int J Clin Exp Pathol. 2009; 2:384-9.
  4. Han JH, et al. Mammaglobin expression in lymph nodes is an important marker of metastatic breast carcinoma. Arch Pathol Lab Med. 2003; 127:1330-4.
  5. Zafrakas M, et al. Expression analysis of mammaglobin A (SCGB2A2) and lipophilin B (SCGB1D2) in more than 300 human tumors and matching normal tissues reveals their co-expression in gynecologic malignancies. BMC Cancer. 2006; 6:88.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: breast carcinoma
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

25 mL predilute280R-10
0.1 mL concentrate280R-14
0.5 mL concentrate280R-15
1 mL concentrate280R-16
1 mL predilute280R-17
7 mL predilute280R-18

For in vitro diagnostic (IVD) use in Canada

25 mL predilute280R-10
0.1 mL concentrate280R-14
0.5 mL concentrate280R-15
1 mL concentrate280R-16
1 mL predilute280R-17
7 mL predilute280R-18

For in vitro diagnostic (IVD) use in Europe

25 mL predilute280R-10
0.1 mL concentrate280R-14
0.5 mL concentrate280R-15
1 mL concentrate280R-16
1 mL predilute280R-17
7 mL predilute280R-18

For research use only (RUO) in Japan

25 mL predilute280R-10-RUO
0.1 mL concentrate280R-14-RUO
0.5 mL concentrate280R-15-RUO
1 mL concentrate280R-16-RUO
1 mL predilute280R-17-RUO
7 mL predilute280R-18-RUO

 

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