PLAP (NB10) Mouse Monoclonal Antibody

PLAP
PLAP (NB10) on classical seminoma.

PLAP (NB10) Mouse Monoclonal Antibody

Specialties: Genitourinary (GU) Pathology

Updated: 2017-05-24 08:46:09

Placental Alkaline Phosphatase (PLAP) belongs to a family of four isozymes that are synthesized in primordial germ cells and in term placental syncytiotrophoblasts.1 Anti-PLAP may be useful in the identification of germ cell tumors.2-4

  1. Fishman L, et al. Developmental phase-specific alkaline phosphatase isoenzymes of human placenta and their occurrence in human cancer. Cancer Res. 1976; 36:2268-73.
  2. Stinghen ST, et al. Specific immunoassays for placental alkaline phosphatase as a tumor marker. J Biomed Biotechnol. 2006; 56087:1-8.
  3. Ravenni N, et al. A human monoclonal antibody specific to placental alkaline phosphatase, a marker of ovarian cancer. MAbs. 2014; 6:86-94.
  4. Jacobsen GK, et al. Placental alkaline phosphatase in testicular germ cell tumours and in carcinoma-in-situ of the testis. An immunohistochemical study. Acta Pathol Microbiol Immunol Scand A. 1984; 92:323-9.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: placenta
  • Dilution Range: 1:50-1:200*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate321M-14
0.5 mL concentrate321M-15
1 mL concentrate321M-16
1 mL predilute321M-17
7 mL predilute321M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate321M-14
0.5 mL concentrate321M-15
1 mL concentrate321M-16
1 mL predilute321M-17
7 mL predilute321M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate321M-14
0.5 mL concentrate321M-15
1 mL concentrate321M-16
1 mL predilute321M-17
7 mL predilute321M-18

For research use only (RUO) in Japan

0.1 mL concentrate321M-14-RUO
0.5 mL concentrate321M-15-RUO
1 mL concentrate321M-16-RUO
1 mL predilute321M-17-RUO
7 mL predilute321M-18-RUO

 

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