Villin (CWWB1) Mouse Monoclonal Antibody

Villin
Small bowel mucosa is labelled by villin antibody in the spiral region.

Villin (CWWB1) Mouse Monoclonal Antibody

Specialties: Gastrointestinal (GI) Pathology

Updated: 2017-05-24 08:46:09

Villin is an actin-binding glycoprotein that serves an important role in the maintenance  of of the  microvilli brush border in gastrointestinal (GI) mucosal epithelium and its associated tumors.1,2 Recent immunohistochemical studies with villin have shown that villin is not only expressed in carcinomas of the gastrointestinal tract, but also in renal cell carcinomas, pancreatic carcinomas, endometrial carcinomas, as well as carcinomas of the ovary and lungs.2 In addition, positive villin expression may be seen in neuroendocrine/carcinoid tumors of the GI tract and lungs.3

  1. Suh N, et al. Value of CDX2, villin, and alpha-methylacyl coenzyme A racemase immunostains in the distinction between primary adenocarcinoma of the bladder and secondary colorectal adenocarcinoma. Mod Pathol. 2005; 18:1217-22.
  2. Tamboli P, et al. Colonic adenocarcinoma metastatic to the urinary tract versus primary tumors of the urinary tract with glandular differentiation: a report of 7 cases and investigation using a limited immunohistochemical panel. Arch Pathol Lab Med. 2002; 126:1057-63.
  3. Zhang PJ, et al. Immunoexpression of villin in neuroendocrine tumors and its diagnostic implications. Arch Pathol Lab Med. 1999; 123:812-6.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic, membranous
  • Control: colon
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate346M-14
0.5 mL concentrate346M-15
1 mL concentrate346M-16
1 mL predilute346M-17
7 mL predilute346M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate346M-14
0.5 mL concentrate346M-15
1 mL concentrate346M-16
1 mL predilute346M-17
7 mL predilute346M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate346M-14
0.5 mL concentrate346M-15
1 mL concentrate346M-16
1 mL predilute346M-17
7 mL predilute346M-18

For research use only (RUO) in Japan

0.1 mL concentrate346M-14-RUO
0.5 mL concentrate346M-15-RUO
1 mL concentrate346M-16-RUO
1 mL predilute346M-17-RUO
7 mL predilute346M-18-RUO

 

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