Villin (CWWB1) Mouse Monoclonal Antibody
Specialties: Gastrointestinal (GI) Pathology
Villin is an actin-binding glycoprotein that serves an important role in the maintenance of of the microvilli brush border in gastrointestinal (GI) mucosal epithelium and its associated tumors.1,2 Recent immunohistochemical studies with villin have shown that villin is not only expressed in carcinomas of the gastrointestinal tract, but also in renal cell carcinomas, pancreatic carcinomas, endometrial carcinomas, as well as carcinomas of the ovary and lungs.2 In addition, positive villin expression may be seen in neuroendocrine/carcinoid tumors of the GI tract and lungs.3
- Suh N, et al. Value of CDX2, villin, and alpha-methylacyl coenzyme A racemase immunostains in the distinction between primary adenocarcinoma of the bladder and secondary colorectal adenocarcinoma. Mod Pathol. 2005; 18:1217-22.
- Tamboli P, et al. Colonic adenocarcinoma metastatic to the urinary tract versus primary tumors of the urinary tract with glandular differentiation: a report of 7 cases and investigation using a limited immunohistochemical panel. Arch Pathol Lab Med. 2002; 126:1057-63.
- Zhang PJ, et al. Immunoexpression of villin in neuroendocrine tumors and its diagnostic implications. Arch Pathol Lab Med. 1999; 123:812-6.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic, membranous
- Control: colon
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 4.0 (CMC34621040)
Have a different keycode?
Click Here
Learn how to obtain your SDS
Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 346M-14 |
| 0.5 mL concentrate | 346M-15 |
| 1 mL concentrate | 346M-16 |
| 1 mL predilute | 346M-17 |
| 7 mL predilute | 346M-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 346M-14 |
| 0.5 mL concentrate | 346M-15 |
| 1 mL concentrate | 346M-16 |
| 1 mL predilute | 346M-17 |
| 7 mL predilute | 346M-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 346M-14 |
| 0.5 mL concentrate | 346M-15 |
| 1 mL concentrate | 346M-16 |
| 1 mL predilute | 346M-17 |
| 7 mL predilute | 346M-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 346M-14-RUO |
| 0.5 mL concentrate | 346M-15-RUO |
| 1 mL concentrate | 346M-16-RUO |
| 1 mL predilute | 346M-17-RUO |
| 7 mL predilute | 346M-18-RUO |
To request information on this product in additional countries, please click the button below.