TAG-72 antibody labels the cytoplasm of colon adenocarcinoma in a somewhat variable fashion.
TAG-72 (B72.3) Mouse Monoclonal Antibody
Specialties: Anatomic Pathology
Updated: 2017-06-02 08:17:23
Tumor associated glycoprotein (TAG)-72 is a high molecular weight glycoprotein that is present on the surface of many neoplastic cells, including adenocarcinomas of the breast, colon, and lung.1-5 TAG-72 is found in lung adenocarcinoma and is absent in mesothelioma, making the TAG-72 antibody useful in distinguishing adenocarcinoma from mesothelioma.5
- Thor A, et al. Distribution of oncofetal antigen tumor-associated glycoprotein-72 defined by monoclonal antibody B72.3. Cancer Res.1986; 46:3118-24.
- Johnston WW, et al. Use of a monoclonal antibody (B72.3) as a novel immunohistochemical adjunct for the diagnosis of carcinomas in fine needle aspiration biopsy specimens. Hum Pathol. 1986; 17:501-13.
- Lundy J, et al. Monoclonal antibody B72.3 as a diagnostic adjunct in fine needle aspirates of breast masses. Ann Surg. 1986; 203:399-402.
- Kline TS, et al. Monoclonal antibody B72.3. An adjunct for evaluation of suspicious aspiration biopsy cytology from the breast. Cancer. 1989; 63:2253-56.
- Ordóñez NG. Am J Surg Pathol. The immunohistochemical diagnosis of mesothelioma: a comparative study of epithelioid mesothelioma and lung adenocarcinoma. 2003; 27:1031-51.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic
- Control: lung adenocarcinoma
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 5.0 (CMC33728050)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 337M-84 |
| 0.5 mL concentrate | 337M-85 |
| 1 mL concentrate | 337M-86 |
| 1 mL predilute | 337M-87 |
| 7 mL predilute | 337M-88 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 337M-84 |
| 0.5 mL concentrate | 337M-85 |
| 1 mL concentrate | 337M-86 |
| 1 mL predilute | 337M-87 |
| 7 mL predilute | 337M-88 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 337M-84 |
| 0.5 mL concentrate | 337M-85 |
| 1 mL concentrate | 337M-86 |
| 1 mL predilute | 337M-87 |
| 7 mL predilute | 337M-88 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 337M-84-RUO |
| 0.5 mL concentrate | 337M-85-RUO |
| 1 mL concentrate | 337M-86-RUO |
| 1 mL predilute | 337M-87-RUO |
| 7 mL predilute | 337M-88-RUO |
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