TAG-72 (B72.3) Mouse Monoclonal Antibody

TAG-72
TAG-72 antibody labels the cytoplasm of colon adenocarcinoma in a somewhat variable fashion.

TAG-72 (B72.3) Mouse Monoclonal Antibody

Specialties: Anatomic Pathology

Updated: 2017-06-02 08:17:23

Tumor associated glycoprotein (TAG)-72 is a high molecular weight glycoprotein that is present on the surface of many neoplastic cells, including adenocarcinomas of the breast, colon, and lung.1-5 TAG-72 is found in lung adenocarcinoma and is absent in mesothelioma, making the TAG-72 antibody useful in distinguishing adenocarcinoma from mesothelioma.5

  1. Thor A, et al. Distribution of oncofetal antigen tumor-associated glycoprotein-72 defined by monoclonal antibody B72.3. Cancer Res.1986; 46:3118-24.
  2. Johnston WW, et al. Use of a monoclonal antibody (B72.3) as a novel immunohistochemical adjunct for the diagnosis of carcinomas in fine needle aspiration biopsy specimens. Hum Pathol. 1986; 17:501-13.
  3. Lundy J, et al. Monoclonal antibody B72.3 as a diagnostic adjunct in fine needle aspirates of breast masses. Ann Surg. 1986; 203:399-402.
  4. Kline TS, et al. Monoclonal antibody B72.3. An adjunct for evaluation of suspicious aspiration biopsy cytology from the breast. Cancer. 1989; 63:2253-56.
  5. Ordóñez NG. Am J Surg Pathol. The immunohistochemical diagnosis of mesothelioma: a comparative study of epithelioid mesothelioma and lung adenocarcinoma. 2003; 27:1031-51.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: lung adenocarcinoma
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate337M-84
0.5 mL concentrate337M-85
1 mL concentrate337M-86
1 mL predilute337M-87
7 mL predilute337M-88

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate337M-84
0.5 mL concentrate337M-85
1 mL concentrate337M-86
1 mL predilute337M-87
7 mL predilute337M-88

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate337M-84
0.5 mL concentrate337M-85
1 mL concentrate337M-86
1 mL predilute337M-87
7 mL predilute337M-88

For research use only (RUO) in Japan

0.1 mL concentrate337M-84-RUO
0.5 mL concentrate337M-85-RUO
1 mL concentrate337M-86-RUO
1 mL predilute337M-87-RUO
7 mL predilute337M-88-RUO

 

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