| Desmin |  |
Anti-Desmin antibody detects a protein that is expressed by cells of normal smooth, skeletal and cardiac muscles. The light microscope has suggested that Desmin is primarily located at or near the periphery of Z lines in striated muscle fibrils. In smooth muscle, Desmin interconnects cytoplasmic dense bodies with membrane bound dense plaques. Anti-Desmin antibody reacts with leiomyomas, rhabdomyomas, and perivascular cells of glomus tumors of the skin (if they are of myogenic nature). This antibody is used to demonstrate the myogenic components/derivation of tumors.
Mouse Monoclonal, Clone: D33
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Regulatory Status
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