| Cytokeratin 5 & 6 |  |
Anti-CK 5&6 positivity is seen in nearly 100% of malignant mesotheliomas and in nearly 0% of lung adenocarcinomas. Anti-CK 5&6 positivity can be seen in undifferentiated large cell carcinoma as well as squamous carcinoma, and has been useful in recognizing spindle cell squamous cell carcinoma of the skin. Less that 10% of carcinomas of the breast, colon, and prostate stain positively for this marker. Anti-CK 5&6 has also been used successfully as a myoepithelial cell marker in the prostate and breast to determine malignancy.
Mouse Monoclonal, Clone: D5 and 16B4
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Regulatory Status
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