
| CD45 (LCA) | ![]() |
Anti-Leukocyte Common Antigen (Anti-LCA) monoclonal antibody is routinely used to aid the differential diagnosis of undifferentiated neoplasms, whenever malignant lymphoma is suspected by the morphological or clinical data. It is a highly specific antibody therefore a positive result is highly indicative of lymphoid or myeloid origin. Certain types of lymphoid neoplasms may lack CD45 (Hodgkin's disease, some T-cell lymphomas and some leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes, erythrocytes and plasma cell precursors.
Mouse Monoclonal, Clone: 2B11 & PD7/26
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Regulatory Status
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