| PAX-5 |  |
PAX-5 encodes for B-cell-specific activator protein (BSAP), a marker for B-cells, including B-lymphoblastic neoplasms and maturation stage. It is found in most cases of mature and precursor B-cell non-Hodgkin's lymphomas/leukemias. In approximately 97% of cases of classic Hodgkin's lymphoma, Reed-Sternberg cells express PAX-5. PAX-5 is not detected in multiple myeloma and solitary plasmacytoma, making it useful for such differentiation. Diffuse large B-cell lymphomas do express PAX-5 save for those with terminal B-cell differentiation. T-cell neoplasms do not stain with anti-PAX-5. There is a strong association with CD20 expression.
Rabbit Monoclonal, Clone: SP34| | 0.1 ml concentrated | 312R-14 | | | 0.5 ml concentrated | 312R-15 | | | 1 ml concentrated | 312R-16 | | | 1 ml prediluted | 312R-17 | | | 7 ml prediluted | 312R-18 | | | 5 Positive Control Slides | 312S | | |
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Regulatory Status
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Mouse Monoclonal, Clone: 24| | 1 ml prediluted | 312M-17 | | | 7 ml prediluted | 312M-18 | | | 15 ml prediluted | 312M-19 | | | Ventana®* dispenser | 760-4270 | | | 5 Positive Control Slides | 312S | | | |
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